According to the Detroit Free Press, Miguel Cabrera has said he will be playing third base. I don't know how well that will work out and normally I would be against such a move. However, they get so little offense out of Brandon Inge/ Don Kelly, it can't hurt to try it. That will be quite an infield both offensively...and defensively. Perhaps, they can move Cabrera to designated hitter when sinker baller Rick Porcello is on the mound.
Now, for another new line-up:
The DH/LF combo is still a big question mark, but I imagine they'll be trying a few players in those spots with Delmon Young perhaps moving back and forth.